Maternal-Fetal Flow, Negative Events, and Preeclampsia
نویسندگان
چکیده
منابع مشابه
Maternal-fetal flow, negative events, and preeclampsia: role of ACE I/D polymorphism.
The risk for an adverse pregnancy outcome is markedly higher in women with history of preeclampsia. This may stem from impaired placentation in early gestation and from high impedance to flow in uteroplacental circulation. The renin-angiotensin system is one of the mediators of the remodeling of spiral arteries throughout pregnancy. The D allele of the Insertion/Deletion (I/D) polymorphism in t...
متن کاملMaternal and Fetal Consequences of Preeclampsia
About 6 to 8 percent of all pregnancies, especially primigravidae is complicated by preeclampsia, a classical triad of elevated blood pressure, proteinuria and edema. Maternal and neonatal morbidity and mortality are of utmost concern as the etiology of preeclampsia is uncertain. At-risk pregnant women can be suspected if they are primigravidae, multiparous, obesed, diabetic, hypertensive, or i...
متن کاملMaternal-fetal interactions, predictive markers for preeclampsia, and programming.
During pregnancy close interactions between the maternal system and the fetal system via the placenta exist that result in a powerful crosstalk between both individuals. Looking for predictive biomarkers in maternal blood is extremely difficult because of this crosstalk as such markers may be derived from only maternal sources, only placental sources or both. In particular, the concentrations o...
متن کاملMaternal-fetal metabolism in normal pregnancy and preeclampsia.
Adaptation to pregnancy in humans involves major anatomic, physiologic and metabolic changes in the mother in order to support and provide for the nutritional and metabolic needs of the growing conceptus. Metabolically, pregnancy is marked by several important and dynamic adjustments including increased insulin resistance, hyperlipidemia and changes in protein and amino acid metabolism. In gene...
متن کاملQuantitative abnormalities of fetal DNA in maternal serum in preeclampsia.
BACKGROUND There is much recent interest in the biologic and diagnostic implication of cell-free non-host DNA in the plasma and serum of human subjects. To determine if quantitative abnormalities of circulating non-host DNA may be associated with certain pathologic processes, we used circulating fetal DNA in preeclampsia as a model system. METHODS We studied 20 preeclamptic women and 20 contr...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2003
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000063146.40351.ad